Selank

Name: Selank
SKU: 64
Price: 35.00 USD
Availability: InStock

$35.00

A synthetic seven-residue peptide derived from the immunomodulatory sequence of tuftsin, stabilized by a C-terminal Pro-Gly-Pro motif, supplied as sterile lyophilized powder for in-vitro neuropharmacology research.

Tested by Freedom Diagnostics TestingHPLC purity + LC-MS identityLot-matched COA on-site

For research use only. This product is a laboratory research chemical. It is not for human or veterinary use, not a drug, supplement, or food, and not intended to diagnose, treat, cure, or prevent any disease. Sold only to qualified researchers and institutions.

Category: Cognitive & Hormonal

Description
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What is Selank?

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro, or TKPRPGP) derived from the immunopeptide tuftsin. The addition of a C-terminal Pro-Gly-Pro motif confers resistance to enzymatic degradation, extending the molecule’s activity relative to the native four-residue tuftsin parent. Developed in Russia, it is studied as an anxiolytic and nootropic research peptide and is not approved in the United States or European Union.

Research areas where laboratories buy Selank for in vitro and preclinical work include anxiety-related behavioral models in rodents (elevated plus maze, open field), GABA-A receptor and GABAergic neurotransmission assays, BDNF and neurotrophin expression studies in hippocampal cultures, enkephalinase-inhibition and regulatory-peptide stability assays, immunomodulation studies leveraging the tuftsin parent sequence, and monoamine balance and gene-expression profiling under defined conditions.

Every lot, independently verified

Independently third-party tested and matched to the lot ID printed on your vial. Values below are from the latest released lot.

99.88%

HPLC-UV Purity

Passed full QC panel

independent third-party lab (Freedom Diagnostics Testing) accredited lab

Latest batch · tested 10 Feb 2026 · Freedom Diagnostics (USA)

Lot details

ProductSelank 11 mg

LotPer-batch on COA

AppearanceWhite lyophilized powder

Accession #2602060019

Reported10 Feb 2026

Full QC panel · ISO 170257 assays

Purity (HPLC-UV)99.88% ✓

Identity (LC-MS)Selank ✓

HPLC conformity (2×)Confirmed ✓

Net content10.06 mg ✓

Heavy metals (ICP-MS)Not Detected ✓

SterilityNo Growth ✓

Endotoxin (USP <85>)Within limits ✓

Every lot is released against Koi’s full QC panel — HPLC purity, LC-MS identity, net content, heavy metals, sterility, and endotoxin — by an independent ISO/IEC 17025-accredited laboratory. Values shown are from the latest released lot and vary batch to batch; the lot-specific certificate is published in our public COA library and matched to the lot ID printed on the vial.

Compound information

Chemical & structural reference data — specifications, molecular profile and handling.

Product Specifications

CompoundSelank (synthetic heptapeptide tuftsin analog)

Vial size11 mg

Purity≥99% by HPLC

Identity confirmationMass spectrometry

FormWhite lyophilized powder

Appearance after reconstitutionClear, colorless solution

ManufacturingSynthesized and lyophilized in the United States

Quality testingIndependent independent third-party laboratory release

Molecular Profile

SequenceThr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)

Molecular formulaC₃₃H₅₇N₁₁O₉

Molecular weight751.90 g/mol

CAS number129954-34-3

ParentTuftsin (Thr-Lys-Pro-Arg)

Structure classSynthetic heptapeptide · Pro-Gly-Pro stabilized

Storage & Handling

AppearanceWhite lyophilized powder

SolubilitySterile water · neutral pH

Storage · powder−20 °C, desiccated, dark (−80 °C long-term)

In solution2–8 °C; aliquot & freeze, avoid freeze-thaw

Selank Mechanism of Action

Stabilized analog of the immunopeptide tuftsin — the C-terminal Pro-Gly-Pro motif confers resistance to enzymatic degradation, extending activity relative to native tuftsin.
Modulates GABAergic neurotransmission, the proposed basis for its anxiolytic profile in rodent models.
Influences brain-derived neurotrophic factor (BDNF) expression in hippocampal tissue.
Inhibits enkephalin-degrading enzymes, prolonging the activity of endogenous regulatory peptides.
Modulates monoamine (serotonin/dopamine) balance and expression of inflammation- and immunity-related genes.
Retains tuftsin-like immunomodulatory activity, distinguishing it from receptor-targeted anxiolytics.

Selank Research Applications

Anxiety-related behavioral models in rodents (elevated plus maze, open field).
GABA-A receptor and GABAergic neurotransmission assays.
BDNF and neurotrophin expression studies in hippocampal cultures.
Enkephalinase-inhibition and regulatory-peptide stability assays.
Immunomodulation studies leveraging the tuftsin parent sequence.
Monoamine balance and gene-expression profiling under defined conditions.

Why Buy Selank from Koi Peptides?

Every batch of Koi Selank is synthesized and lyophilized in the United States, then released against independent third-party laboratory (Freedom Diagnostics Testing) testing.
Each lot is tested by HPLC for purity, LC-MS for identity confirmation, and endotoxin assay for sterility readiness.
The lot ID is printed on every vial and ties back to a public COA library, so researchers can verify documentation before they buy and after the vial arrives.
Orders placed before 2 PM CT ship the same business day, and shipping is free on orders over $200.

Kozlovskaya, M. M., et al. (2003). Anxiolytic activity of the synthetic peptide Selank. Bulletin of Experimental Biology and Medicine, 136(5), 488–491.
Volkova, A., et al. (2016). Selank and its effect on the GABAergic and monoaminergic systems. Journal of Psychopharmacology.
Kolomin, T., et al. (2014). Effect of Selank on gene expression of inflammation and immunity in rat brain. Peptides.
Semenova, T. P., et al. (2007). Tuftsin analog Selank: anxiolytic and nootropic properties. Regulatory Peptides.

Regulatory Status

FDA, WADA anti-doping, and compounding status — provided for research context.

FDA StatusSelank is not approved by the FDA for any indication. It was developed in Russia and is not approved in the United States or European Union. It is an unapproved research compound that has not been evaluated by the FDA for safety or efficacy. The research-grade material supplied by Koi Peptides is synthesized for in vitro laboratory research only — not formulated, packaged, or labeled for human use, and not authorized for any human or veterinary indication.

WADA Anti-Doping StatusSelank is not currently named on the WADA Prohibited List. As with all compounds, athletes and researchers should consult the current WADA List directly, since classifications are reviewed annually. This information is provided for research context only and does not constitute compliance advice.

Compounding Pharmacy StatusKoi Peptides is a chemical research supplier — not a compounding pharmacy or outsourcing facility under sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act — and supplies no compounded preparations of any kind. As an unapproved research compound, Selank is not eligible for pharmacy compounding for human use.

Disclaimer

For research use only. Not for human or veterinary use. Selank is supplied to qualified research professionals for in vitro laboratory study. It has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease. Koi Research Labs LLC is a chemical supplier, not a compounding pharmacy under 503A nor an outsourcing facility under 503B of the Federal Food, Drug, and Cosmetic Act. By purchasing, the buyer agrees this material will not be introduced into humans or animals. Misuse may violate federal, state, or local laws.

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